The invention discloses an epidemic-prevention quick culling machine for dead bodies of animals and birds. The epidemic-prevention quick culling machine is characterized by comprising a stirring fermentation tank, wherein a transmission shaft is arranged in the stirring fermentation tank; a plurality of stirring pulverizers are arranged on the transmission shaft; a pulverizing knife pair is arranged on each stirring pulverizer; the transmission shaft is driven to operate by a drive motor outside the stirring fermentation tank; an electromagnetic heater is arranged on the bottom of the stirring fermentation tank; a cover cap is arranged on the top of the stirring fermentation tank; a cabin door at a discharging end of a charging and conveying device is arranged on the upper side wall of the stirring fermentation tank; a discharging device is further arranged on the bottom of the stirring fermentation tank; and a discharging port of the discharging device is connected to a screening device. The epidemic-prevention quick culling machine for dead bodies of animals and birds can be used for quickly treating the dead bodies of the animals and the birds and eliminating the dead bodies of the animals and the birds at the source, so that the dead bodies of the animals and the birds in a production process of the animal husbandry are timely disposed, and therefore, the phenomena that the environment is polluted by disease transmission and necrosis and the food safety is endangered by illegal business due to scattering of dead bodies of the animals and the birds are prevented. Meanwhile, the dead bodies of the animals and the birds are treated to obtain regenerative biological diesel and organic fertilizer resource.