The invention belongs to the technical field of experiments of high-temperature steam oxidation and creep and particularly relates to a method and a system for realizing interaction of the high-temperature steam oxidation and the high-temperature creep. The method is characterized in that a high-temperature steam circulation channel is arranged in a sample, holes are formed in an upper pull rod and a lower pull rod of a creep machine, the sample is communicated and connected with the upper pull rod and the lower pull rod of the creep machine to form a gas channel, and the circulation of high-temperature steam in the channel is realized by external devices; the sample is externally heated, and axial load is applied to the sample, so as to realize the high-temperature creep; and the high-temperature steam realizes the circulation in a circulation loop, so as to reduce the usage amount. The method can be used for the performance evaluation on materials when a combined action of the creep and the high-temperature steam oxidation is considered, researching the influence of the high-temperature steam oxidation to the creep performance and the influence of creep behaviors to the high-temperature steam oxidation, and relatively truly and effectively reflecting a high-temperature mechanical performance evolution law of the material in a serving stage, thereby providing theoretical foundations for the safe and reliable operation of the device.