The invention provides a cotton/viscose glue and acetate mixed fabric dyeing and finishing process. The dyeing and finishing process is carried out in a jig and comprises steps of: fabric pretreatment, dyeing processing and fabric aftertreatment. The fabric pretreatment comprises steps of: singeing, desizing and bleaching. The fabric aftertreatment comprises steps of: softening and sizing, calendaring and shrinkage. According to the invention, cotton/viscose glue and acetate fiber mixed fabric is dyed by a mesothermal one-bath one-step method. Colors are not mutually stained. The process provided by the invention has advantages of differential dyeing, simple equipment requirement, simple and feasible process and color control, energy saving and emission reduction and green and environmentally friendly dyeing and finishing processing. By the adoption of the process, fabric design style, color, pattern effects are fully presented, variable-pigment stereo effect of high-grade cotton/viscose glue/acetate fiber mixed figured cloth is highlighted, novelty is increased, and novel fabric dyeing and finishing matching technology requirements and market requirements are met.