The invention discloses an anti-icing nano functional wire. The wire is provided with a layer of an aluminum substrate (1). A lower honeycomb aluminum oxide layer (21) and an upper honeycomb aluminum oxide layer (22) are stacked on the upper layer of the aluminum substrate (1). Diameters of upper honeycomb holes (42) of the upper honeycomb aluminum oxide layer (22) are smaller than those of lower honeycomb holes (41) of the lower honeycomb aluminum oxide layer (21), so that the upper honeycomb aluminum oxide layer (22) can plug the lower honeycomb aluminum oxide layer (21). Besides, the lower honeycomb holes (41) are filled with mixed nanoparticles formed by mixing nano heating functional particles, nano phase transition particles and nano polyelectrolyte particles. The wire achieves an anti-icing effect by heating spontaneously or reducing a water condensation point, the structure and properties are stable, the binding force of the wire with the aluminum substrate is good, and the wire is reliably protected. After the wire is connected to a current, the anti-icing effect is remarkable, so that the wire is popular with users.