The invention relates to a polymer charged cleaning method of transformer station 220-kilovolt high voltage electric power equipment, an organic solution based on polymer micro-releasing mechanism effects is utilized to serve as an insulation cleaning agent. When a transformer station operates, the insulation cleaning agent is chosen to be sprayed through an insulation spray gun or the insulation cleaning agent is chosen to be sprayed through the insulation spray gun to be matched with an insulation electric cleaning brush to clean according to different voltage classes, field arrangements, dirty types and dirt accumulation degrees of the electric power equipment, and charged cleaning for the corresponding electric power equipment is achieved. The polymer insulation cleaning agent has high insulation, has not flashing points, is free from combustion and easy to volatilize and environment-friendly, can clean comprehensive dirt of dust, greasy dirt, salt and the like of the high voltage electric power equipment safely, sufficiently and effectively, and therefore the pollution flashover accident rate is effectively reduced, and generation of pollution flashover accidents of a power grid is eliminated.