The invention provides a semi-transparent semi-reflecting liquid crystal display panel and a manufacturing method thereof, and a liquid crystal display device. The semi-transparent semi-reflecting liquid crystal display panel comprises a first substrate, a second substrate, a liquid crystal layer, a transmittance area and a reflecting area, wherein the second substrate is opposite to the first substrate, the liquid crystal display layer is disposed between the first substrate and the second substrate, and the transmittance area and the reflecting area are arranged between the first substrate and the second substrate. The manufacturing method of the semi-transparent semi-reflecting liquid crystal display panel includes: forming a first horizontal orientation layer on the first substrate; forming a second orientation layer corresponding to the first horizontal orientation layer in the area on the second substrate, corresponding to the transmittance area; and forming a vertical orientation layer corresponding to the first horizontal orientation layer in the area of the second substrate, corresponding to the reflecting area. Orientation is performed by light orientation technology, no friction procedure is adopted, the manufacturing method belongs to a clean mode, and two-domain orientation is achieved under simplest process conditions.