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发明公开
CN103298941A 苍白密螺旋体三联抗原 无效 - 驳回 复审申请

苍白密螺旋体三联抗原
摘要：
本发明公开了苍白密螺旋体三联抗原构建体，其包括三种苍白密螺旋体抗原(TP15、TP17和TP47)，以及十氨基酸前导序列(标签261)和人铜锌超氧化物歧化酶(hSOD)。这种构建体对于梅毒感染的体外诊断是最佳化的。本发明还公开了含有编码三联抗原的DNA的质粒、宿主细胞、生产方法、检测方法和试剂盒。
摘要（英）：

A Treponema pallidum triplet antigen construct is disclosed which includes three Treponema pallidum antigens (TP15, TP17, and TP47), as well as a ten amino acid leader sequence (tag 261) and human copper zinc superoxide dismutase (hSOD). This construct is optimized for in vitro diagnosis of syphilis infection. Plasmids containing DNA encoding the triplet antigen, host cells, production methods, detection methods, and kits are also disclosed.

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