The invention discloses a servo control device and an operation and control method for a jacquard loom. According to the operation and control method for the jacquard loom, the operation state of a loom spindle is monitored in real time by utilizing a spindle angle sensor, a rotation weak current detection signal of the loom spindle is timely transferred to a controller, and the weak current detection signal is amplified and driven by utilizing the controller and is output to a serve motor so as to control the serve motor to drive a loom jacquard shaft to work so as to realize tracking operation of the loom jacquard shaft and the loop spindle. According to the servo control device, the conventional mechanical connection and driving manner is changed; the structure is simple, the efficiency is high, the mounting and the maintaining are convenient, and the reliability is high; the damage of cone teeth during a use process is avoided, the production and use costs are saved, and the safety of the production is guaranteed.