The invention relates to response equipment provided with a pluggable control module based on a demand response and a response method. The response equipment comprises a main controller module, a voltage and current sampling module, an electric energy measuring module, a non-electric-parameter collecting module, a peripheral interface module, a communication module, a storage module, the pluggable control module, a liquid crystal display module and a power source module. The response method comprises the steps that the response equipment receives demand response information of a demand response main station; the response equipment receives non-electric parameters, electric parameters and environment information of energy-using equipment or a system; the response equipment outputs control signals based on a control strategy; the energy-using equipment or the system receives the control signals; a control unit in the energy-using equipment or the system generates control action; the response equipment returns a demand response result to the demand response main station. The response equipment is provided with a unified pluggable interface, hot plug of the control module is supported, targeted control over specific energy-using equipment or the system is conducted conveniently, and the good effect is achieved.