The invention discloses a high-power LED lamp cooling device and a manufacturing method thereof. The manufacturing method is characterized in that a semiconductor crystal bar for manufacturing N-type semiconductor elements or P-type semiconductor elements is manufactured into a circular-cone-shaped crystal bar, wherein one end of the circular-cone-shaped crystal bar has a large diameter, and the other end of the circular-cone-shaped crystal bar has a small diameter; then, when the semiconductor crystal bar with a circular cone shape is sliced, a color mark number is marked on a large-diameter end surface of the tail end of each wafer; and a circular conical surface of each wafer is cut and pelletized to obtain the N-type semiconductor elements or the P-type semiconductor elements with polygonal cylinder shapes, the N-type semiconductor elements and the P-type semiconductor elements are arranged between two beryllium oxide ceramic wafers comprising conductive circuits in a matrix arrangement manner, a head end of each list of the N-type semiconductor elements and a tail end of each list of the P-type semiconductor elements are connected in series, and the high-power LED lamp cooling device is manufactured. The high-power LED lamp cooling device and the manufacturing method have the advantages of good cooling effect, high work efficiency, low energy consumption, capabilities of reducing luminous decay of an LED lamp and prolonging the service life of the high-power LED lamp and the like.