This invention relates to a traditional Chinese medicine composition for the treatment of menopausal uterine fibroids and applications thereof. The traditional Chinese medicine composition consists of the following parts by weight of bulk drugs: 30-40 parts of Radix Arnebiae Seu Lithospermi, 40-50 parts of gypsum rubrum, 15-20 parts of prunella vulgaris, and 20-30 parts of hedyotis diffusa. The traditional Chinese medicine composition is advantageous by conforming to " sovereign, minister, assistant and courier " principle in ingredient combination, having clinical trials-verified effects of significantly reducing the size of uterine fibroids, alleviating clinical symptoms of patients suffer from uterine fibroids, and improving the quality of life of patients. No adverse drug reaction is found, and the traditional Chinese medicine composition has little toxic and side effects, relatively few bulk drugs and good curative effects, thus being suitable for long-term administration, and is a safe and effective mixture for the treatment of menopausal uterine fibroids.