The invention discloses a drug for curing hepatitis and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The drug comprises following effective raw materials: whitebackleaf mallotus root, iris japonica thumb, alum, lygodium japonicum, salix matsudana koidz, herb of shady groundsel, triquetrous tadehagi herb, flying squirrel feces, artemisia japonica, fortune holly fern rhizome, phellodendron, hypecoum erectum, cornus officinalis, sago seed, turtle shell and fiveleaf akebia fruit. The drug has the functions of nourishing liver, clearing heat, removing toxicity and tranquilizing by nourishing the heart, and has prominent curative effects on inhibiting and clearing hepatitis virus, adjusting human immunity functions, recovering liver form and functions, and preventing and curing hepatic fibrosis and liver cancer. The drug has the advantages of low cost, user-friendliness, easy absorption, and quick and good curative effect, achieves the goal of curing both the symptom and the root causes, and has no side or toxic effects and a very good curative effect on hepatitis.