The invention relates to a zinc-oxide piezoresistor raw material, a preparation method thereof and a piezoresistor. The zinc-oxide piezoresistor raw material comprises the following components by mole percent: 91.48-98.03% of zinc oxide, 0.5-2.0% of bismuth trioxide, 0.5-2.5% of silicon dioxide, 0.35-1.5% of cobaltosic oxide, 0.5-1.0% of manganese carbonate, 0.1-0.5% of chromium oxide, 0.01-2.0% of yttria and 0.0001-0.001% of aluminium nitrate. The zinc-oxide piezoresistor raw material does not antimony, and due to the silicon dioxide, the characteristic of the piezoresistor is improved, the surface state density is increased, the voltage gradient, the barrier height and the nonlinear coefficient are improved, the leakage current is reduced and the current impact resistance is enhanced; due to the yttria, the conductivity, the current impact resistance, the nonlinear coefficient and the voltage gradient are improved, the limiting voltage rate and the leakage current are reduced, the grain growth is inhibited and the zinc-oxide piezoresistor has higher voltage gradient and excellent electrical property.