The invention discloses a remote configuration method of a safety interlock. The remote configuration method comprises the following steps that (1) object addressing adopts combined judgment logic, and an objective identify label is jointly confirmed through an IP (Internet Protocol) address/ port number and an equipment ID; (2) a client side requires an HTTP (Hyper Text Transport Protocol) data stream for configuration containing information of a user name and a password, and the configuration is encryptedly transmitted to a server side; (3) the accessing of the data by a server side configuration process adopts a Biba model, a process entity and a data entity are graded, and data access is controlled strictly and hierarchically; (4) pilot run dynamic measurement technology is adopted for creditability of a system of the device, and whether the configuration is modified or not is judged by analyzing pilot run input and output data; and (5) remote configuration adopts a responsive architecture, after the server side completes configuration, result information is encoded and fed back to the client side. The remote configuration method of the safety interlock has the remarkable advantages that maintenance personnel can remotely operates the safety interlock to complete upgrade, so that time and labor force are saved, the operation is simple, the implementation stability is high, and the safety is high.