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发明公开
CN103402993A 用于疾病治疗的4，9-二羟基-萘并[2,3-b]呋喃新型酯 无效 - 驳回 转让

用于疾病治疗的4，9-二羟基-萘并[2,3-b]呋喃新型酯
摘要：
本发明公开了4,9-二羟基-萘并[2,3-b]呋喃酯以及其制备方法和用法。本发明还公开了将该类酯在体内转换成具有治疗活性的4,9-二羟基-萘并[2,3-b]呋喃。本发明还进一步公开了包含4,9-二羟基-萘并[2,3-b]呋喃酯的药物组合物以及其用于治疗包括增生性疾病在内的各种病症。
摘要（英）：

The present invention discloses esters of 4,9-dihydroxy-naphtho[2,3-b]furans and methods of making and using the same. The present invention also discloses conversion of the esters into therapeutically active 4,9-dihydroxy-naphtho[2,3-b]furans in vivo. The present invention furthermore discloses pharmaceutical compositions comprising the esters of 4,9- dihydroxy-naphtho[2,3-b]furans for the treatment of various indications including proliferative diseases.

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