The invention discloses a hot fogging concentrate containing arasan and azoxystrobin, and a preparation method of the fogging concentrate. The hot fogging concentrate comprises the following raw materials in percentage by weight: 20-35 percent of arasan, 2-8 percent of azoxystrobin, 3-5 percent of hot fog density conditioning agent, 2-4 percent of botanical fungiticide, 6-8 percent of surface-active agent, 0.1-1 percent of foam killer, and the balance of smoke agent. The hot fogging concentrate is a broad-spectrum fungiticide, is used in combination with a hot fog machine, can be used for controlling and curing plant diseases, has the advantages of high pesticide applying efficiency and good effe, is suitable for plants with middle-height and low-height stalks, such as oilseed rape, corn and wheat, is high in hot fog controllability, and generates less environment pollution. Through the adoption of the hot fogging concentrate, the labor intensity of operators can be lowered, contamination risks can be reduced, and the problem of plant disease control in water-deficient areas can be can solved completely.