The invention provides a traditional Chinese medicine composition for supporting chemo-treatment. The composition comprises the following components: pangolin scales, membranous milkvetch root, curcuma aromatica, grape leaf, ginseng, radix linderae, giant knotweed, calculus bovis, laminaria, nostoc commune, cactus, pearl, realgar, croci stigma, centipede, bittersweet herb, trichosanthes root, black nightshade, radix rehmanniae recen, verbena, white paeony root, ganoderma, rhizome sparganii, fructus evodiae, puccoon, andrographis paniculata, deerhorn glue, bulb of edible tulip, daphne giraldii nitsche, and ramie root. The composition provided by the invention has the advantages of quick curative effect, high efficiency and small side effect aiming to the side effects caused by chemo-treatment.