The invention provides a drive circuit, a method, a shifting register, a pixel unit and a display unit. The drive circuit comprises a drive amplifying module, a touch screen drive module, and a time-share drive control module. The time-share drive control module sends out time-share drive control signals according to first control signals and second control signals. According to the time-share drive control signals, he drive amplifying module drives an OLED in the OLED drive period, amplifies touch screen sensor output signals in the touch screen drive period, and controls the touch screen drive module to drive a touch screen according to touch screen control signals and amplified touch sensor output signals. The drive circuit respectively conducts time-share drive on the OLED and the touch screen so as to be capable of driving the OLED and the touch screen with few components and be capable of effectively avoiding mutual crosstalk between OLED drive signals and touch screen drive signals.