The invention relates to an edible mushroom culture material and a production method of the edible mushroom culture material. The edible mushroom culture material comprises, by weight, 30-100 parts of Chinese medicine residues, 10-60 parts of sorghum shells, 5-50 parts of corn flour and 1-15 parts of quick lime. Through the steps of smashing, sterilization, inoculation, fruiting and managing, edible mushrooms are cultivated. The cultivated edible mushrooms are free of poison and innocuousness, has edible safety and can solve the problem of waste treatment and achieve successes on environment and economy.