The invention discloses an angiography machine enabling laser positioning to be convenient. The angiography machine comprises a C-shaped arm and a cross laser used for emitting cross-line-shaped lasers, the C-shaped arm is arranged on a C-shaped arm plane, the angiography machine further comprises a supporting box with a bottom opening, the supporting box is fixedly connected with the C-shaped arm through a cross rod, an adjusting device capable of moving longitudinally and transversely in the supporting box is arranged in the supporting box, and the moving plane of the adjusting device is perpendicular to the C-shaped arm plane. The cross laser is arranged on the adjusting device, and stretches downwards out of the bottom opening of the supporting box, the laser output direction of the cross laser is parallel to the C-shaped arm plane, the longitudinal and transverse movement of the adjusting device drives the cross laser to move to be parallel to the C-shaped arm plane, and therefore the position of the cross-line-shaped lasers is adjusted. The angiography machine enables one of cross-line-shaped lasers emitted by the cross laser to be always parallel to the C-shaped arm plane of the angiography machine, and the position of the cross point of the cross-line-shaped lasers emitted by the cross laser can be adjusted conveniently and accurately.