The invention discloses a load curve alternating injection-based intelligent power distribution network scheduling system and a load curve alternating injection-based intelligent power distribution network scheduling method. According to the method, when an operation mode is generated, an adaptive power supply scheme is adopted for loads of different time intervals in consideration of difference of a workday load curve and a rest-day load curve, the reliability of power supply and the adaptability to load are improved, the network loss is reduced as much as possible, and the economy of power supply is improved. The generation of the operation mode is more flexible compared with the original strategy, and the utilization rate of power distribution equipment is practically improved.