The invention discloses a moisture sensing and permeable film, a moisture sensing and permeable apparatus, a fruit and vegetable box and a refrigerator. Under high humidity conditions, moisture in the fruit and vegetable box is exhausted, so that dew formation is prevented; and under low humidity conditions, moisture in the fruit and vegetable box is prevented from escaping, so that the fruit and vegetable box is capable of preventing wet rot of vegetables caused by dew formation, and maintaining freshness of fruit and vegetable. The moisture sensing and permeable film (4) is prepared by coating a cellulose substrate (5) with regenerated cellulose, and opening parts (5a) of the cellulose substrate is totally covered by regenerated cellulose films, wherein moisture permeation amount of regenerated cellulose changes according to the change of humidity. The fruit and vegetable box is provided with the moisture sensing and permeable film; under low humidity conditions, the moisture permeation amount is reduced by using the fruit and vegetable box; and under high humidity conditions, the moisture permeation amount is increased by using the fruit and vegetable box, so that no dew is formed in the sealed fruit and vegetable box, and the freshness of fruit and vegetable can be maintained for a long time under high humidity conditions. In addition, one characteristic of regenerated cellulose is that an amorphous structure of regenerated cellulose reversibly changes according to the change of humidity. When humidity in the fruit and vegetable box is reduced, the moisture permeation amount is reduced, so that higher humidity can be maintained.