The invention relates to the technical field of electric power cables, in particular to an intelligent substation optical cable connection automatic design method based on a virtual-true mapping mode. Connection of virtual terminals of all IEDs is automatically judged, physical deployment information of an existing device is combined, a virtual-true mapping rule is adopted, and therefore optical cable connection relations and tail cable connection relations are generated. The method is mainly suitable for designers of an electric power design institute to use aided design tool software to complete design of an intelligent substation in design effort. According to the method, optical cable connection, tail cable connection and the like can be automatically generated through a substation cell at an early stage, screen cabinet configuration and configuration of an IED physical port, a switch physical port and an optical distribution frame physical port in a screen cabinet by combination of completed connection work of the virtual terminals, and thus the workload and error probability in the aspect of intelligent substation cable design are greatly reduced, design efficiency is improved, and errors caused by manual design are reduced.