The present invention relates to a process comprising at least one reactive trituration step which consists in putting an oil cake comprising from 3% to 30% oil in contact with an anhydrous light alcohol and an alkaline catalyst under temperature and time conditions that are sufficient to allow for the extraction and transesterification of the vegetable oil and lead to the production of a mixture comprising fatty acid esters and glycerol, and a de-oiled cake comprising less than 3% oil. The present invention also relates to a detoxified de-oiled cake as well as to a mixture of fatty acid esters with improved stability and resistance to oxidation.