The invention discloses an intelligent monitoring system of air conditioners of a transformer substation. The intelligent monitoring system comprises a plurality of environment temperature and humidity monitoring terminals, a plurality of air conditioner control terminals, a plurality of power quality monitoring terminals, a control substation and a control server. Each transformer substation is correspondingly provided with one control substation, and each air conditioner in switch chambers and control chambers of the transformer substation is correspondingly provided with one environment temperature and humidity monitoring terminal, one air conditioner control terminal and one power quality monitoring terminal. The environment temperature and humidity monitoring terminals, the air conditioner control terminals and the power quality monitoring terminals are all connected with the control server through the control substation, the environment temperature and humidity monitoring terminals, the air conditioner control terminals and the power quality monitoring terminals are in RS485 communication with the control substation, and the control substation is in MIS network communication with the control server. The intelligent monitoring system of the air conditioners of the transformer substation enables intelligent sensing, infrared remote control and remote communications to be integrated, and the intelligent capacity of the transformer substation is improved.