The invention relates to a one-step molding combined mold for specially-shaped workpieces. The one-step molding combined mold comprises an upper mold plate, a lower mold plate, a spindle hole, an upper module, a base, a lower module, an injection molding cavity, a side mold plate, a side mold block, and an upper mold guiding block, wherein the upper mold plate and the lower mold plate after being assembled are pressed continually in order to guide and press the lower mold downwards; four corners of the lower end in the lower mold are provided with a plurality of limiting guide rods in a sliding guiding manner; the plurality of limiting guide rods are axially fixed on the base for limiting the press direction and the press distance of the lower mold; a plurality of axial thin guide rods are fixedly arranged in the middle of the base among the plurality of limiting guide rods; a plurality of through holes are formed on the position, corresponding to the lower mold plate and the lower module, of the plurality of thin guide rods; and a hole or blind hole is formed in the injection molding cavity of the position corresponding to the thin guide rods. The mold provided by the invention is simple in structure, reasonable in design, high in machining efficiency, long in service life, preferable in structural stability, high in machining precision and wide in application scope, is convenient to strip; and furthermore, due to the adoption of the mold, the machining efficiency is improved, and the machining quality is effectively guaranteed.