The invention discloses a transformer vibration isolation and noise reduction device. The transformer vibration isolation and noise reduction device comprises steel rails, vibration reduction springs, shock absorption layers and transformer bases, wherein matched grooves are formed in a base and a top cover of each steel rail, the vibration reduction springs are embedded in the grooves, each shock absorption layer is laid on the top cover of the corresponding steel rail, and each transformer base is fixedly arranged on the upper portion of the corresponding shock absorption layer. The transformer vibration isolation and noise reduction device has the advantages that due to the fact that the springs and rubber cushions are arranged, duel vibration isolation and sound isolation are achieved, high-frequency vibration, low-frequency vibration and solid sound transmission are greatly reduced, and the phenomenon of echo resonance produced between floors of a transformer substation is avoided, and due to the fact that mechanical shock of transformers is reduced, the service life of the device is prolonged, and meanwhile the noise reduction effect of the underground transformer substation can meet the environment requirement.