The invention discloses a mesh cleaning system used for a multi-cylinder long mesh paper machine, and belongs to the field of accessories of paper making process production equipment. High-pressure water pipes are divided into two sets, each high-pressure water pipe is connected with a row of high-pressure spraying devices, one set of the high-pressure water pipes are installed on the inner side of a shaping mesh of the multi-cylinder long mesh paper machine, the other set of the high-pressure water pipes are installed on the outer side of the shaping mesh of the multi-cylinder long mesh paper machine, high-pressure spraying elements are installed on a breast roll of the shaping mesh, a first guide roll of the shaping mesh, a couch roll of the shaping mesh and other positions, and the number of the high-pressure spraying elements is increased by 200%-500% than that of high-pressure spraying elements of a traditional multi-cylinder long mesh paper machine with the same width and the same speed. The mesh cleaning system has the advantages that efficient front flushing and efficient reverse flushing of the shaping mesh are achieved, service life of the shaping mesh is prolonged, quick high-quality dehydration of high padding paper pulp is guaranteed, and shaping of paper sheets is retained and promoted. Problems of a traditional mesh cleaning system are solved.