The invention discloses a spare power automatic switching cooperation control method of a substation area. The spare power automatic switching cooperation control method comprises the following steps: spare power automatic switching on high-pressure side is started, meanwhile spare power automatic switching on low-pressure side is paused, and if a spare power automatic switching action on high-pressure side succeeds, a spare power automatic switching action on low-pressure side does not occur due to busbar voltage recovery on low-pressure side; if the spare power automatic switching action on the high-pressure side fails, the spare power automatic switching action on low-pressure side is accelerated; when power on the high-pressure side in the substation area is not lost and power on the low-pressure side is lost, the spare power automatic switching action on low-pressure side is accelerated. By adopting the spare power automatic switching cooperation control method, relevant information of spare power automatic switching at upper and lower stages on the high-pressure side and the low-pressure side of a transformer substation can be interacted, a full-station spare power automatic switching function is optimized and improved, and the power supply recovery time during failure occurrence is shortened.