The invention discloses an adjusting-free and self-checking method for a station domain protection control device in an intelligent transformer substation. The method comprises the following steps: utilizing the uniqueness of the MAC(Media Access Control)addresses and the allocated IP (Internet Protocol) addresses of devices in the intelligent transformer substation to distinguish whole-station protection equipment objects, acquiring the fixed value parameters of on-site protection devices in the substation by the station domain protection control device through a transformer substation MMS (Multimedia Messaging Service) network, automatically mapping and downloading the acquired fixed value parameters of the on-site protection devices to corresponding fixed values of the station domain protection control device according to different addresses by the station domain protection control device, and simultaneously realizing the automatic verification of fixed value content which is successfully downloaded by the station domain protection control device. When the station domain protection control device normally runs, the fixed value content of each on-site protection device is polled at regular time, and an online monitoring function is realized. When updating variation occurs in the on-site protection fixed values, the variation of the on-site protection fixed values is discovered by the station domain protection control device through a polling mechanism, the existing fixed value content is updated in an self-adaptive way, and the parameters are corrected. The method has the advantages that the manual operation is reduced, and the use reliability and flexibility of the device are improved.