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发明公开
CN103719021A 1号染色体替换野生小家鼠品系C57BL/6.枣庄2-Chr1的构建 失效 - 权利终止

1号染色体替换野生小家鼠品系C57BL/6.枣庄2-Chr1的构建
摘要：
本发明涉及1号染色体替换野生小家鼠C57BL/6.枣庄2-Chr1的建立。构建了一种新的染色体C57BL/6替代实验小鼠品系，该小鼠品系的遗传背景以C57BL/6小鼠为主，但其中1号染色体以枣庄2小鼠为主。本发明的染色体替换品系可用于研究在相同基因组背景下，由不同的1号染色体基因组带来的性状差异，是采用遗传学方法研究染色体基因组功能的有用工具。
摘要（英）：

The invention relates to construction for Chromosome 1 to replace wild mus musculus strain C57BL/6. Zaozhuang 2-Chr1. A novel Chromosome C57BL/6 replacing experiment musculus strain is constructed, a C57BL/6 musculus is mainly used as the genetic background of the musculus strain, and a Zaozhuang 2 musculus is mainly used in the Chromosome 1. The Chromosome replacing strain can be used for studying character difference brought by different Chromosome 1 genomes under the background of the same genome, and a useful tool for studying the functions of the genomes by using a genetics method is achieved.

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