The invention relates to a production method of a tackifying encapsulation agent for a drilling fluid, and belongs to the technical field of petrochemical industry. The tackifying encapsulation agent is prepared from acrylamide (AM), acrylic acid kalium (AAK), 2-acrylamide-2-methyl propane sulfoacid (AMPS) and epoxypropyl trimethyl ammonium chloride by quaternary copolymerization synthesis through the adoption of an opposite phase emulsifying polymerization process, has good tackifying and encapsulating effects, is good in temperature resisting performance, suitable for a water-based drilling fluid, and particularly suitable for a water-based drilling fluid without a solid phase or a clay phase, and shows relatively strong tackifying and encapsulating abilities in brine slurry such as organic salt and kali salt.