The invention discloses a pipeline sealing installation method. The method comprises the following steps: butt joint positions of a pair of pipelines are respectively provided with turnup; double faced adhesive tape is adhered to one side of a sealing strip; the sealing strip is pasted on the turnup of any pipeline in the two butt joint pipelines through the double faced adhesive tape, and is arranged around the turnup for one circle with any point of the turnup as a starting point; after the head end and the tail end of sealing strip are connected, the turnup of the two pipelines are in butt joint with each other, and the sealing strip is arranged between the turnup of the two pipelines; the butt joint turnup of the two pipelines is fixedly connected and is locked in a relative mode so as to extrude the sealing strip. According to the method, the sealing strip is arranged between flanges, and a sealing effect is achieved through extrusion. The sealing strip is formed through stretching Teflon in the radial direction and extruding Teflon, so that a sealing ring has good malleability and tensile property, is good in sealing effect, strong in anti-corrosion property, weather fastness and wear-resisting property, and capable of being long unlimitedly, and the condition that die sinking cannot be completed due to the fact that the diameter of an air duct is too large does not exist.