The invention discloses a paddy-upland rotation planting method of greenhouse potherbs. The method includes the following steps: selecting a first potherb variety from land potherb varieties to plant in a greenhouse; selecting a second potherb variety from the land potherb varieties, and interplanting the second potherb variety and the first potherb variety in the greenhouse; selecting a third potherb variety from the land potherb varieties, and applying fertilizer and interplanting the third potherb variety in row spacing after the first potherb variety stops growing and before the first potherb variety is eradicated; after the third potherb variety germinates, eradiating the first potherb variety; after the second potherb variety stops growing, eradiating the second potherb variety and planting the third potherb variety; after the third potherb variety stops growing, selecting a fourth potherb variety form the land potherb varieties, and building shallow water layers to transplant the fourth potherb variety after applying fertilizer; after the fourth potherb variety stops growing, selecting a fifth potherb variety from aquatic potherb varieties to plant; after the fifth potherb variety stops growing, repeated the above steps to plant circularly.