The invention discloses a pressure resistance testing system for high-altitude protection equipment. The pressure resistance testing system comprises a pressure storage container (1), a testing container (2), a separation door (5) and a blasting and decompression power device (6), wherein the pressure storage container (1) is used for providing pressure with pre-set height; the testing container (2) is used for containing tested high-altitude protection equipment, is in sealed connection with the pressure storage container, and comprises an inner bottleneck (3) for releasing the pressure; the inner bottleneck is internally and fixedly provided with a blasting and decompression separation membrane (4) covering the end face of the whole bottleneck; the separation door (5) is arranged between the testing container and the pressure storage container and is used for separating or communicating the pressure storage container and the testing container; the blasting and decompression power device (6) comprises a firing pin (7) for breaking the blasting and decompression separation membrane by colliding so as to enable the pressure in the testing container to achieve the pressure with the pre-set height; the firing pin of the blasting and decompression power device can instantly break the blasting and decompression separation membrane by the colliding, so that the pressure in the testing container can instantly achieve the pressure with the pre-set height, and the pressure-resisting capability of the high-altitude protection equipment under the instant pressure loss can be tested very well.