This invention relates to a piezoelectric nanometer generator, an eyeball moving monitor sensor and a monitor method. The piezoelectric nanometer generator comprises a lower electrode layer, a first insulation layer positioned on the upper surface of the lower electrode layer, a piezoelectric layer positioned on the upper surface of the first insulation layer, and an upper electrode layer positioned above the piezoelectric layer. The thickness of the generator is less than 20 Mum. The flexible piezoelectric nanometer generator is constructed by utilizing the piezoelectric properties possessed by piezoelectric thin film materials and the eyeball moving monitor sensor is manufactured based on the piezoelectric nanometer generator. The ultrathin flexible piezoelectric generator is attached on the surface of the eyelid. When the eyeball is moving, the pressure applied by the eyeball on the eyelid changes constantly along the moving, which causes the stress on the eyelid to change, and the change acts on the piezoelectric generator so as to output electric signals to the outside. The eyeball moving monitor sensor disclosed by the invention can perform long time monitor on human eyes, and is low in cost, easy for carrying and simple in structure.