The invention relates to a method for controlling an application program of a mobile device and a use method. The method for controlling the application program of the mobile device comprises the following steps that: whether the mobile device is knocked is detected; and if it is detected that the mobile device is knocked, the application program stored in the mobile device is controlled. Since the application program in the mobile device can be controlled through sensing the knock received by the mobile device, a user can control corresponding application programs through knocking the mobile device under a situation in which the user is inconvenient to operate the application programs through a touch screen or buttons.