The invention provides wild grape wine with functions of producing saliva and nourishing the stomach and a production method thereof. The wine takes wild grapes, Chinese yam, coastal glehnia root, dried longan pulp, Chinese dates, lotus seeds, mulberries, fragrant solomonseal rhizome, lily, almonds and hawthorns as main raw materials. The production method comprises the main process flows of material selection, drying, mixing, soaking, packaging and finished product preparation. The wine has the advantages of health care, spleen and stomach tonifying, qi benefiting and saliva producing, quick effect, pure natural property, no toxic or side effect and the like, has good auxiliary treatment effects on main diseases such as loss of appetite, discomfort due to nausea and the like and is suitable for drinking.