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发明公开
CN103834699A 使用改进量的氯和钾在微藻类中产生高水平的DHA 无效 - 驳回 复审申请

使用改进量的氯和钾在微藻类中产生高水平的DHA
摘要：
本发明公开了通过海洋微生物，包括异养的海洋沟鞭藻类隐甲藻，使用低水平的氯离子产生高度不饱和的脂肪酸的方法。具体地，通过控制钠离子和钾离子水平在低氯培养基中生长海洋微生物增加高度不饱和的脂肪酸产量的方法。本发明也涉及通过海洋生物在低pH水平产生高度不饱和的脂肪酸的方法，并包括产生耐受低pH的菌株的方法。
摘要（英）：

Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.

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