The invention belongs to the technical field of structural engineering, and relates to a modularized multi-story and high-rise assembly type steel structure frame center supporting system formed by assembling assembly type floors, assembly type flange columns and assembly type sway braces through bolts. Each assembly type floor comprises a board A, a board B and a board C. The assembly type floors are spliced through bolts to form a floor of a whole layer of a building. Beam and column nodes of the steel structure system and connection between the sway braces and a framework are welded in a factory, the rigid connection of the nodes can be achieved effectively, welding quality is ensured, and structural stress is facilitated. The modularized multi-story and high-rise assembly type steel structure frame center supporting system achieves industrialized production, can be rapidly assembled on site, increases the construction speed, shortens the construction period, lowers building cost of projects and reduces pollution to environment, and steel can be recycled after the supporting system is disassembled, so that the supporting system is an environment-friendly structural system.