The invention discloses a method and a device for processing printing documents. The method is applied to a first system corresponding to a first process of digital printing. The first system is connected with a second system corresponding to a second process of the digital printing. The first system is different from the second system. The method includes acquiring selection information of the second process and demand information used for generating large-edition documents meeting the requirements of the second process; selecting N documents from M documents according to the selection information; converting the N documents into J first transplantable documents; converting the J first transplantable documents into K large-edition documents corresponding to the second process according to the demand information. The M is an integer larger than or equal to 1, the N is a positive integer smaller than or equal to the M, the J is an integer larger than or equal to the N. The K large-edition documents have large-edition document information correspondingly, and the K is an integer larger than or equal to 1.