The invention provides a high-speed rail wireless special network cell switching optimal switching point determining method based on source-destination eNodeB (evolved Node B) throughput for the selecting problem of the optimal switching reference point of a high-speed rail fixed point switching algorithm. A train loads downlink full-load service, implements fixed point switching processes for every switching reference point, records the difference value between throughputs in certain periods before and after switching, operates train records for a plurality of times and calculates the average difference value between the throughputs of every preset candidate switching reference point before and after switching, and selects the point with the lowest difference value of the system throughput before and after switching as the optimal switching reference point. In engineering, the optimal switching reference points can be determined for the entire high-speed rail through the high-speed rail wireless special network cell switching optimal switching point determining method based on the source-destination eNodeB throughput and under a geographic-position-based switching method. The high-speed rail wireless special network cell switching optimal switching point determining method based on the source-destination eNodeB throughput can solve the rapid switching problem in a high-speed moving environment, reduce the number of times of call dropping, improves the switching success rate and enhances the service quality of high-speed broadband mobile services.