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发明公开
CN103959065A 预测肿瘤对抗ERBB3抗体的应答 有权 许可

预测肿瘤对抗ERBB3抗体的应答
摘要：
本发明公开一种用于定量预测人类肿瘤对使用ERBB3抑制剂(例如抗ERBB3抗体)的处理是敏感的还是抗性的诊断方法。该方法是基于测量NRG1在由肿瘤得到的组织样品中的RNA水平或蛋白质水平的表达。
摘要（英）：

A diagnostic method for predicting quantitatively whether a human tumor will be sensitive or resistant to treatment with an ERBB3 inhibitor, e.g, an anti-ERBB3 antibody, is disclosed. The method is based on measurement of NRG1 expression at the RNA level, or at the protein level, in a tissue sample from the tumor.

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