The invention discloses a gas extraction hole drilling hole sealing technology in a manner of two-end self-blocking and under pressure. A hole drilling inner hole sealing device is utilized, the manner that a two-end self-blocking hole sealing bag grouts and seals a hole under pressure is adopted, and a hole sealing material is used for extracting gas, drilling the hole and sealing the hole; the length of a bedding hole drilling hole sealing section is 5-8 m, and the length of a perforative-layer hole drilling hole sealing section is not less than 5 m. With adoption of the technology, the hole sealing cost is low, the hole sealing air impermeability is high, the use is simple, convenient and rapid, positioning hole sealing can be realized, and the gas extraction hole drilling hole sealing efficiency is greatly improved; the traditional hole sealing technology is innovated in the terms of the hole sealing material, the hole sealing device and the hole sealing parameters.