The invention discloses a cultivation method of a new strain of quickly-grown Portuguese oysters with golden yellow shells. The cultivation method comprises the following steps: setting a breeding goal, establishing a breeding system, purifying the new strain and the like. Specifically, the golden yellow shells of the Portuguese oysters and full weight are taken as breeding goals, the breeding system is established through a group breeding and family breeding method, and the new strain of quickly-grown Portuguese oysters with golden yellow shells is screened through continuously directional purification with several generations. The new strain of Portuguese oysters bred through continuous breeding with several generations has the advantages of high growth, golden yellow shells, high commodity value and the like, and is suitable for monomer oyster cultivation and uncooked oyster production, so that the method has important roles in improving the cultivation yield, commodity value and economic benefit of the Portuguese oysters.