The invention relates to a side punching and shaping mold for a knee protection support. The side punching and shaping mold comprises an upper mold and a lower mold, wherein the lower mold comprises a lower mold body, a lower mold base plate, a lower mold plate, a wedge lower mold plate, a puncher chip fixing seat, a wedge horizontal push plate, a plunger chip, a reset spring, a No. 1 screw, a lower positioning pin, a side limit plate and a wedge guide plate; the upper mold comprises an upper mold plate, an upper mold base plate, a wedge upper base plate, a pressing plate which is matched with the lower mold body, a wedge vertical pressing plate which is matched with the bevel of the wedge horizontal push plate, a No. 2 screw, an upper positioning pin, an equal-altitude screw and an elastic element. The side punching and shaping mold for the knee protection support has the advantages that the structural design is reasonable, the operation and control are convenient, the manufacturing cost is low, and the like, and adapts to the outer contour of the knee protection support, the precise positioning and the side punching are thus realized, the automatic separation is realized, convenience is provided for an operator, the side punching and processing period is shortened, and the production efficiency is improved.