The invention discloses a mechanical and pneumatic combined balance-type remote gas pressure regulator. The pressure regulator mainly consists of a valve body, a valve core, a diaphragm and a mechanical and pneumatic regulating mechanism, wherein the valve core is arranged in the valve body; the diaphragm and the mechanical and pneumatic regulating mechanism are arranged on the valve body. The mechanical and pneumatic regulating mechanism is arranged on the valve body, and matched with the diaphragm; the diaphragm is regulated through mechanical pressure and/or air pressure, and then, pressure in the working chamber of the valve body is regulated and balanced. According to the gas pressure regulator, by effectively combining the mechanical regulation control mechanism and the air source control mechanism, pressure regulation is performed, and the gas pressure regulator can also be used for realizing remote control regulation on external air sources.