The invention discloses an extraction method for operation data of a power grid regulation and control integration system. The method comprises the steps that a model mapping file is extracted from the power grid regulation and control integration system, wherein the model mapping file comprises a serial number, a measurement identification, a measurement Chinese name, a factory station name, an equipment name, an equipment type and a measurement type; the operation data of the power grid regulation and control integration system are monitored in real time, change measurement data in the operation data are extracted, and a holographic time scale data file is generated in combination with the occurrence moment of the change measurement data, wherein the holographic time scale data file comprises the occurrence moment of the change measurement data, the number of the change measurement data at the moment and the change measurement data at the moment; the change measurement data are jointly composed of the measurement identification, a measurement value and a measurement quality code. According to the extraction method for the operation data of the power grid regulation and control integration system, all the power grid operation data are extracted, the data truly reflect the actual operation status of a power grid, and later-stage data analysis and application are facilitated.