The invention discloses a resonance boost DC/DC converter and a control method thereof suitable for high-voltage and high-power occasions. The converter is connected with a direct-current input power source and a load and comprises two primary-side diodes, a first switching tube, a second switching tube, a third switching tube, a fourth switching tube, a resonance unit, a first rectifier diode, a second rectifier diode and two filter capacitors. The resonance boost DC/DC converter is characterized in that the resonance unit is connected with a bridge arm composed of the four switching tubes and a rectifier unit composed of the two rectifier diodes and the two filter capacitors. According to the resonance boost DC/DC converter and the control method thereof, approximate zero voltage switching-off of the switching tubes and zero current switching-off of the rectifier diodes can be achieved, losses can be greatly reduced, and meanwhile the voltage stress of all switching devices is not larger than one second of the output voltage. A resonance circuit can be used for the high-power boost occasions.