The invention discloses a method for removing iron from an iron-containing zinc sulfate solution. The method comprises the following steps: supplying the iron-containing zinc sulfate solution to a vertical reaction kettle, and introducing steam and oxygen into the vertical reaction kettle so as to perform primary iron removal treatment in the vertical reaction kettle to obtain first iron-removed slurry; supplying the first iron-removed slurry to a horizontal reaction kettle, and introducing steam and oxygen to the horizontal reaction kettle so as to perform secondary iron removal treatment in the horizontal reaction kettle to obtain second iron-removed slurry. According to the method of removing iron from the iron-containing zinc sulfate solution disclosed by the embodiment of the invention, the vertical reaction kettle and the horizontal reaction kettle are combined for use so as to effectively solve the production interruption caused by the problems of scaling in the kettles in the iron removal process and ensure the continuous and stable operation of production, thereby significantly improving the iron removal efficiency and the equipment utilization rate.